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  • Student profile: Olivia Ballew

Student Profile: Olivia Ballew

Monday, April 15, 2019

Olivia Ballew stops to tie her shoe while out for a run.
Ph.D. candidate Olivia Ballew balances graduate school with training as she prepares for the 2020 Olympic marathon trials. Photo by Matt Dwyer, IU Biology

Ph.D. student balances graduate school with marathon training

In early November 2018, Olivia Ballew qualified for the 2020 Olympic Marathon Trials at the CNO Financial Monumental Marathon in Indianapolis. The trials will be held in Atlanta in February 2020. This gives Ballew the opportunity to compete for a spot on the 2020 Olympic Team. To reach the Olympics, she will have to place among the top three at the trials.

To qualify, Ballew had to run a time of 2:45:00, and she ran the 26.2-mile distance in 2:43:13 (6:14 min/mile pace) at Indianapolis. As of March 8, 2019, there were 285 women in the nation qualified for the marathon trials. (The qualifying window closes on January 19, 2020.)

Olivia Ballew running near a lake in Brown County State Park. The tree leaves are in fall colors of yellow, orange, and red.
Olivia Ballew runs amid the fall colors last year at Brown County State Park. Photo by Ben Meraz

Ballew is a Ph.D. candidate in IU Biology’s Genome, Cell, and Developmental Biology Graduate Program; she is a member of Associate Professor Soni Lacefield’s lab. Ballew’s research focuses on repair of DNA damage, working to better understand how errors in DNA are passed from parent to child.

Ballew explains: “The average human body comprises over 30 trillion cells. These cells must safeguard their genomes throughout their lifetime to prevent diseases and cancer. Additionally, humans must be able to faithfully pass on their genetic information (DNA) to subsequent generations. There are two main mechanisms to divide a cell: meiosis and mitosis. In humans, meiosis produces female eggs and male sperm while mitosis produces the remainder of the cells in the body. Although cells most often faithfully divide, the processes of meiosis and mitosis are not completely error free. Checkpoints are the surveillance mechanisms in cells that sense these errors and delay cell division, allowing the cell time to correct errors. Research into meiotic checkpoints is necessary because errors can lead to developmental disorders and infertility. Similarly, studying mitosis is imperative because many cancer cells have defective checkpoints which allow unrestrained cell division.”

Ballew ran track and cross-country in high school in Roanoke Rapids, North Carolina. Although she received some offers to run in college, she didn’t pursue them. She majored in biology at University of North Carolina where she developed an interest in genetics that led her to study at IU.

Not having run competitively since 2008, Ballew began to train again in late 2016. Remarkably, after only two years of training, she has found herself in the position to compete with some of the country’s fastest marathoners.

Ballew’s days are busy—juggling laboratory work and school with running. She has little time to socialize.

“Olivia comes in to the lab at all hours and is ready to work,” says Lacefield. “Her pure dedication and flexibility to research and running have made her extremely successful. She is the only person I know who could do both.”

Soni Lacefield and Olivia Ballew in the lab.
Olivia Ballew (right) in the lab with her mentor, Soni Lacefield. Courtesy photo

Ballew notes, “Running and science can go hand in hand. I was out for a run at lunch and was thinking about a problem—how can I get this to work? I came up with a solution during my run. You’re always going and going in the lab. It’s hard to find time to just think. Running has given me this outlet.”

Earning a place at the U.S. Olympic Marathon Trials has made all of her sacrifices worthwhile. Ballew, however, is quick to point out that publishing her first research paper was better.

“Qualifying for the trials was good, but seeing my name on a paper as first author was way better,” she says.

Ballew received an IU College of Arts and Sciences Dissertation Research Fellowship that will fund her dissertation. She hopes to complete her Ph.D. next year. In the meantime, her next competition in preparation for the trials will be the Boston Marathon.

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