The cover of the September issue of Cold Spring Harbor Protocols displays an image taken by Tennessen lab graduate student Shefali! The image shows the ventral side of central nervous system (CNS) from third-instar Drosophila larvae (juvenile brain), highlighting the neural stem cells in red and ganglion mother cells in green. The focus of the image has been adjusted to highlight the cellular morphology showing the neuroblast arrangement within the central brain and the optic lobe region. Shefali’s thesis work focuses on understanding how non-autonomous glucose dependent signals can regulate cellular homeostasis within the developing brain. The brain-body axis is a powerful system to study inter-organ metabolic signaling because not only is it conserved in many metazoans, but also has clear implications in diseases like diabetes, neurodegeneration and cancer. Congrats Shefali!
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