Professor, Biology
Director of Graduate Studies, Biology
Simon Hall 019
(812) 856-3633
Tuli Lab website
IU Trustees Teaching Award, 2013
Ever wonder how does a virus coordinate all the steps needed to make a new particle? Our lab studies the viral and host determinants required for alphavirus assembly and spread. Alphaviruses are arboviruses—they are transmitted from a mosquito to a vertebrate—so we focus on how the assembly determinants are conserved or differ in these two hosts. We use a variety of approaches to study assembly including viral and host genetics, cell biology, biochemistry, and structural biology. For details, see our lab website.
Ramsey J, Mukhopadhyay S. 2017. Disentangling the frames, the state of research on the alphavirus 6K and TF proteins. Viruses: 9, 228.
Lazaro GR, Mukhopadhyay S, Hagan MF. 2017. Why enveloped viruses need cores—the contribution of a nucleocapsid core to viral budding. arXiv preprint arXiv:1706.04867.
Ramsey J, Renzi EC, Arnold RJ, Trinidad JC, Mukhopadhyay S. 2017. Palmitoylation of Sindbis virus TF protein regulates its plasma membrane localization and subsequent incorporation into virions. J Virol 91:e02000-16.
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