- Postdoctoral Fellow, Purdue University, 1999-2005
- Postdoctoral Fellow, University of Texas, Southwestern Medical Center, 1996-1999
- Ph.D., University of Illinois at Chicago, 1996
Tuli Mukhopadhyay
Professor, Biology
she/her/hers
- sumukhop@iu.edu
- 812-856-3686
- Simon Hall 220C
- Office Hours
Education
About Tuli Mukhopadhyay
Lab
Simon Hall 019
812-856-3633
Tuli Lab website
Awards
ASM Alice C. Evans Award, 2025
College of Arts and Sciences Distinguished Mentor Award, 2024
Fellow, American Association for the Advancement of Science, 2020
IU Trustees Teaching Award, 2013
Research
Ever wonder how does a virus coordinate all the steps needed to make a new particle? Our lab studies the viral and host determinants required for alphavirus assembly and spread. Alphaviruses are arboviruses—they are transmitted from a mosquito to a vertebrate—so we focus on how the assembly determinants are conserved or differ in these two hosts. We use a variety of approaches to study assembly including viral and host genetics, cell biology, biochemistry, and structural biology. For details, see our lab website.
Research area
Publications
Penn, W. D. and Mukhopadhyay, S. (2022) Abracadabra, One becomes Two: The Importance of Context in Viral -1 Programmed Ribosomal Frameshifting. mBio. 13(4):e0246821.
Ren, S. C., Qazi, S. A, Towell, B., Wang, C-Y, and Mukhopadhyay, S. (2022) Mutations at the Alphavirus E2/E1 inter-dimer interface have host-specific phenotypes. J. Virol. 96:e02149-21.
Button, J. M. and Mukhopadhyay, S. (2021) Capsid-E2 interactions rescue core assembly in viruses that cannot form cytoplasmic nucleocapsid cores. J. Virol. 95:e01062-21.
Harrington, H. R., Zimmer, M. H., Chamness, L. M., Nash, V., Penn, W. D., Miller III, T. F. Mukhopadhyay, S., and Schlebach, J. S. (2020) Cotranslational Folding Stimulates Programmed Ribosomal Frameshiting in the Alphavirus Structural Polyprotein. J. Biol. Chem. 295:6798-6808.
The College of Arts