We use powerful and diverse bacterial systems to study fundamental biological processes.
We use advanced quantitative microscopy techniques to explore the localization and structure of proteins, RNA, DNA and metabolites within the context of the bacterial cell. Our work reveals processes that drive prokaryotic development, differentiation, motility, cell division, and genome replication.
We use powerful, high-throughput genomic approaches, biochemistry, and molecular genetics to study gene regulation in response to environmental change. Our work defines the molecular mechanisms of physiological acclimation, horizontal gene transfer, light color perception, chemical communication, biofilm formation, and responses to nutrient limitation.
We explore the origins of mutation and the social pressures that govern bacterial behavior. Our work illuminates the evolutionary trajectories that shape individual microbial genomes and the microbiome.