Since 1994, the Midwest Microbial Pathogenesis Conference (MMPC) has brought together investigators from the Midwest region of the United States to present and discuss recent advances in the field of microbial pathogenesis. This is the premier regional conference in the Midwest that features talks and poster presentations from new assistant professors, newly recruited senior scientists in the region, and trainees. There is an emphasis to included scientists of all levels that are underrepresented in the field of microbiology. The MMPC provides an excellent opportunity for students, fellows and faculty alike to renew old friendships and make important new contacts. We are pleased to welcome the keynote speaker Kim Orth, PhD, the Earl A. Forsythe Chair in Biomedical Science and a Howard Hughes Medical Institute Investigator at UT Southwestern Medical Center.