Soni Lacefield

Soni Lacefield

Associate Professor, Biology


  • Postdoctoral Fellow, Harvard University, 2003-2008
  • Ph.D., MIT, 2003


MacKenzie AM and Lacefield S. CDK regulation of meiosis: Lessons from S. cerevisiae and S. pombe. Genes (2020, online ahead of print)

Cairo G and Lacefield S. Establishing correct kinetochore-microtubule attachments in mitosis and meiosis. Essays in Biochemistry (2020, online ahead of print).

Cairo G, MacKenzie A, and Lacefield S. Differential requirement of Bub1/Bub3 in the regulation of meiotic versus mitotic chromosome segregation. Journal of Cell Biology 219 (4):e201909136 (2020).

Wang F, Zhang R, Feng W, Tsuchiya D, Ballew O, Li J, Denic V, Lacefield S. Autophagy of an amyloid-like translational repressor regulates meiotic exit. Developmental Cell 52:141-151 (2020).

Ballew O and Lacefield S. The DNA damage checkpoint and the spindle position checkpoint maintain meiotic commitment in Saccharomyces cerevisiae. Current Biology 29: 1-12 (2019).

Lacefield S. Detaching the tether: remodeling mitochondrial localization during meiosis. Journal of Cell Biology. 218(2) (2019).

Barsh GS, Bhalla N, Cole F, Copenhaver GP, Lacefield S, Libuda DE. 2018 PLOS Genetics Research Prize: Bundling, stabilizing, organizing—The orchestration of acentriolar spindle assembly by microtubule motor proteins. PLOS Genetics 14(9):e1007649 (2018).

Gihana GM, Musser TR, Thompson O, and Lacefield S. Prolonged CDK inhibition results in septin perturbations during return-to-growth and mitosis. Journal of Cell Biology (2018).

Lacefield S. Chromosome biology: specification of the kinetochore for cohesion recruitment. Current Biology 27 (24): R1319-R1321 (2017).

Falk JE, Tsuchiya D, Verdaasdonk J, Lacefield S, Bloom K, Amon, A. Spatial signals link exit from mitosis to spindle position. Elife 5. pii:e14036 (2016)

Yang Y, Tsuchiya D, and Lacefield S. Bub3 promotes Cdc20-dependent activation of the APC/C in S. cerevisiae. Journal of Cell Biology 209(4): 519-527 (2015).
This paper was featured in the JCB Biobytes podcast.

Ho KH, Tsuchiya D, Oliger AC, and Lacefield SLocalization and function of budding yeast CENP-A depends on kinetochore protein interactions and is independent of canonical centromere sequence. Cell Reports 9(6): 2027-2033 (2014).
This paper was recommended by F1000.

Tsuchiya D, Yang Y, and Lacefield S. Positive feedback of NDT80 expression ensures irreversible meiotic commitment in budding yeast. PLOS Genetics 10 (6): e1004398 (2014).

Tsuchiya D and Lacefield S. Cdk1 modulation ensures the coordination of cell-cycle events during the switch from meiotic prophase to mitosis. Current Biology 23 1505-1513 (2013).

Tsuchiya D, Gonzalez C, and Lacefield S. The spindle checkpoint protein Mad2 regulates APC/C activity during prometaphase and metaphase of meiosis I in S. cerevisiae. Molecular Biology of the Cell 22 (16): 2848-2861 (2011). This paper was chosen for “Highlights in MBoC” by the editorial board.
This paper was recommended by F1000.

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